This study was conducted to find out the difference among mean scores of optimism for HIV/AIDS patients of different levels of monthly income. The sample consisted of 150 HIV/AIDS patients was collected from the department of medicine, Jawahar Lal Nehru Medical College & Hospital, Aligarh Muslim University, Aligarh, Uttar Pradesh. The Life Orientation Test-Revised (LOT-R) was used. The data was analyzed by using one-way ANOVA. The results showed that there was found a significant difference among people of different levels of monthly income living with HIV/AIDS on optimism.